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Anti-NQO1 Polyclonal Antibody
產(chǎn)品簡(jiǎn)介:

Anti-NQO1 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號(hào):K106519P

更新時(shí)間:2022-08-15

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產(chǎn)品介紹

Anti-NQO1 Polyclonal Antibody

英文名稱Anti-NQO1 Polyclonal Antibody
宿主Rabbit
別名DHQU;DIA4;DTD;NMOR1;NMORI;QR1
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量27kDa
Gene ID1728
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human NQO1
性狀液體
Public Immunogen RangeA synthetic peptide of human NQO1
Subcellular LocationsCytoplasm Cell membrane
Swiss ProtP15559
克隆類型Polyclonal Antibody
背景資料This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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